N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-thiophen-3-yl-D-alanine - Names and Identifiers
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-thiophen-3-yl-D-alanine - Physico-chemical Properties
Molecular Formula | C22H19NO4S
|
Molar Mass | 393.46 |
Density | 1.2174 (rough estimate) |
Melting Point | 184.2 °C |
Boling Point | 626.3°C at 760 mmHg |
Flash Point | 332.6°C |
Vapor Presure | 1.5E-16mmHg at 25°C |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.5060 (estimate) |
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-thiophen-3-yl-D-alanine - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Safety Description | 24/25 - Avoid contact with skin and eyes.
|
WGK Germany | 3 |
HS Code | 29223900 |
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-thiophen-3-yl-D-alanine - Introduction
(R)-N-FMOC-3-Thienylalanine, also known as (R)-N-FMOC-3-Thienylalanine, is a chemical substance with the following properties:
1. Appearance: usually white or similar to white crystalline or powdery solid.
2. Molecular formula: C30H23NO4S
3. Molecular weight: 505.58g/mol
4. Solubility: soluble in organic solvents (such as dimethyl sulfoxide, N,N-dimethylformamide), insoluble in water.
(R)-N-FMOC-3-Thienylalanine main uses are as follows:
1. Peptide synthesis: as a protective group in peptide chemistry, it is used to protect the α-amino group of amino acids, so as to protect the extension of the peptide chain.
2. Drug development: It can be used to synthesize biologically active peptides, proteins and drug molecules for drug research and development.
3. Biochemical research: As a molecular tool, it is used to study biological molecules, enzyme reactions, protein structure and function, etc.
A common method for preparing (R)-N-FMOC-3-Thienylalanine is to react the Fmoc protecting group with D-3-(3-thienyl) alanine through a specific organic synthesis step. Specific synthetic methods can refer to the relevant literature or organic synthesis manual.
Regarding the safety information of (R)-N-FMOC-3-Thienylalanine, the following points should be noted:
1. Avoid inhalation of dust or solution contact with skin and eyes.
2. Use should wear appropriate personal protective equipment, such as gloves, protective glasses and laboratory coat.
3. Follow good laboratory practices, such as a well-ventilated laboratory environment and proper waste disposal.
4. Keep dry and avoid high temperature during use or storage.
Although (R)-N-FMOC-3-Thienylalanine are usually used under laboratory conditions, it is still recommended to use it under safe handling and take appropriate safety precautions according to specific research and application needs.
Last Update:2024-04-09 21:21:28